The Animation Retargeting in Atoms is possible thanks to the characterization of the Agent Types.
A characterization consists of tagging the joint chains of the skeleton by type, subtype, position and posing the rig in a reference pose.

Atoms will transfer the animation of the chains with the same tag set if any matching chain is found during the simulation .

You should always start this process from the scene that you used for exporting the agent type.
Before configuring the joint chains, users should pose the rig in the reference pose, normally the T-pose. Make sure that all the characterization files of your agents (sources and targets) are exported fitting the same reference pose: the more similar the reference poses, the better the retargeting is going to work.

All joints not belonging to a chain will not be considered during the retargeting process.

You have different tags that you can use, as explained below.

The tag type can have the following values:

Root and effector types transfer rotations between characters. 
Clavicle, pelvis, limb and spine also transfer rotations if the chain has less than two joints otherwise, they use an IK algorithm.

Other tags:

In case you have two chains with the same tag combination, and no chain with the same index is found on the source agent type, then the chain with the previous index is used.

From Atoms 4.0, you can set a pole vector for your chains. If no pole vector is provided an automatic pole vector will be evaluated automatically whenever possible. A pole vector should be provided by the user whenever the joints of any limb are on a straight line in bind pose or within an animation.

Please follow the Maya and Houdini tutorials to see how to use this UI.